Cancer on tip of nipple. Corecţie areole şi mameloane en - Clinica Zetta

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    Cancerul Mamar Conținutul We aim to present cases series confirmed with polythelia and introduce a mini-review of the PubMed cancer on tip of nipple. Cases series: Eight adult patients confirmed with sporadic unilateral polythelia on the milk line were included. Left right ratio was three to five.

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    The accessory nipple size was smaller than ortothopic one. No underlying breast anomaly was detected at ultrasound.

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    Anamnesis did not reveal any other significant medical condition to any of the patients. Kajawa classification was applied to all the subjects and revealed areolar polythelia type.

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    None of the patients wanted, neither required cosmetic plastic surgery. General data: Polythelia is identified very early at birth or after different hormonal stimulus as seen during pregnancy, lactation, puberty.

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    Genetic syndromes as Char syndrome include polythelia, but also some other autosomal dominant cancer on tip of nipple involving bone, brain, eye anomalies. A particular high rate of malignant co-morbidities or malformations of the kidneys and or urinary tract is found on a subset of patients with polythelia for instance, for renal, gallbladder, testicular, and prostate cancer.

    Conclusion: Polythelia may be found in current medical practice as a sporadic or familial condition without significance but severe forms are associated with genetic syndromes, uro-genital anomalies and some malignancies, including ectopic breast cancer.

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